Determination of Frequency of Epstein-Barr Virus in Non-Hodgkin Lymphomas Using EBV Latent Membrane Protein 1 (EBV-LMP1) Immunohistochemical Staining
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چکیده
منابع مشابه
Determination of frequency of epstein-barr virus in non- Hodgkin lymphomas Using EBV latent membrane protein 1 (EBV-LMP1) immunohistochemical staining.
BACKGROUND The presence of Epstein-Barr virus (EBV) in Non-Hodgkin's lymphoma can be identified by immunohistochemistry for detection of EBV latent membrane protein (LMP). The role of EBV as an etiologic agent in the development of non-Hodgkin lymphoma has been supported by detection of high levels of latent membrane protein 1 (LMP-1) expression in tumors. However, no study has been conducted i...
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Epstein-Barr virus (EBV) latency has been associated with a variety of human cancers. Latent membrane protein 1 (LMP-1) is one of the key viral proteins required for transformation of primary B cells in vitro and establishment of EBV latency. We have previously shown that LMP-1 induces the expression of several interferon (IFN)-stimulated genes and has antiviral effect (Zhang, J., Das, S. C., K...
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the aim of this work was to see whether tamarin immunisation with recombinant vaccinia virus expressing epstein barr virus latent proteins could prime t cells which were, on activation, able to inhibit the outgrowth of epstein barr virus transformed cells in vitro. the vaccination appeared to be successful as all vaccinated tamarins developed vaccinia lesions. however, the vaccination protocol ...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2013
ISSN: 1513-7368
DOI: 10.7314/apjcp.2013.14.6.3963